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The Nave Controls (NC) were used as the inter-animal controls and were anesthetized for the same amount of time as the other two groups before both hind limbs were harvested, but no muscle stimulation occurred in either limb

Oxidative stress is observed when there is an imbalance between the ROS generation and elimination, due to the impaired antioxidant defence system and/or the exacerbated activity of pro-oxidant enzymes [37]

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Consequently, this design aggravates the redox imbalance, causing a rapid increase in ROS in the short term in vitro, ultimately leading to the downstream signaling pathway activation and apoptosis of AML cells

Indeed, many gut microbes express muscarinic and adrenergic receptors, suggesting that autoantibodies may target these molecules (Furukawa and Haga, 2013